Jaundice is the abnormal accumulation of bilirubin in the body tissues, resulting in yellow discoloration. Familial jaundice is a type of jaundice caused by mutations in the gene UGT-1A that encodes the enzyme uridine diphosphate glucuronosyltransferase.TreatmentLiver transplantation: It is the only therapeutic and definitive therapy. The transplanted liver has no abnormality of conjugation and thus red  Read More

A patient is anemic with low levels of oxygen supplements in the blood. This supplement is hemoglobin, produced by the RBC (Red Blood Cells) of a body. The deficiency of Folate or Vitamin-B12 or B9 defects the production of these RBCs and increases their size abnormally. These dysfunctions RBCs and result in Folate-Deficiency Anemia.Differences in Iron and Folic Acid Deficiency:Iron and folic acid defic  Read More

Pyroglutamicaciduria (PGA) is a rare metabolic disorder that causes high levels of PGA in the blood.Pyroglutamic acid (PA) is an intermediate product of glutamine metabolism.Glutamine is a non-essential amino acid that is abundant in the body and is involved in many metabolic processes.PA is formed from glutamine via transamination reactions involving glutamate dehydrogenase (GDH).PA is e  Read More