About gastroenteritis, eosinophilic

What is gastroenteritis, eosinophilic?

Eosinophilic gastroenteritis is a rare digestive disease characterized by the triad of eosinophilic infiltration of segments of the gastrointestinal tract, abnormalities of gastrointestinal function (varying from dyspepsia and obstruction to diarrhea and ascites) and exclusion of other diseases with peripheral eosinophilia.

What are the symptoms for gastroenteritis, eosinophilic?

Infiltration of the walls of the esophagus symptom was found in the gastroenteritis, eosinophilic condition

Eosinophilic gastroenteritis may affect any part of the gastrointestinal tract from the esophagus to the rectum. Symptoms include dysphagia (sometimes presenting as food impaction), Heartburn, Abdominal pain, Nausea, Vomiting, Diarrhea, Weight loss, and Bloating (ascites is possible). The eosinophilic infiltration may involve one or more layers of the gastrointestinal wall. The particular symptoms present in each person depend upon the layer and the location of involvement. Most commonly, the stomach wall and the small bowel are involved. Mucosal involvement leads to protein-losing enteropathy and malabsorption. Muscle layer involvement causes Abdominal pain, Vomiting, dyspeptic symptoms and bowel obstruction. Subserosal involvement predominantly causes ascites with marked eosinophilia. Sometimes eosinophilic pleural effusion is present. Eosinophilic gastroenteritis is a chronic, waxing and waning condition.

What are the causes for gastroenteritis, eosinophilic?

The exact cause of eosinophilic gastroenteritis is unknown. Some cases of this disease may be caused by a hypersensitivity to certain foods or other unknown allergens. Often, a family history of allergy is present. Atopy (asthma, hay fever or eczema) is present in a subset of patients. Food allergies are common.

What are the treatments for gastroenteritis, eosinophilic?

Eliminating foods to which a person is allergic may prove helpful in some cases. The corticosteroid drug prednisone is usually an effective treatment for eosinophilic gastroenteritis. Sometimes budesonide can be helpful. Immunosuppressive drugs like azathioprine may be worth trying. Surgery may be necessary in severe cases in which there is an obstruction of the intestines. Other treatment is symptomatic and supportive.

What are the risk factors for gastroenteritis, eosinophilic?

Eosinophilic gastroenteritis (EGE) is a rare form of an inflammatory disorder. It occurs due to the infiltration in the walls of the intestine that affect the small intestine and the stomach. Under EGE, any part between the esophagus and the rectum of the gastrointestinal tract may get affected. This EGE can further be classified into muscular, mucosal, and serosal.
According to several types of research performed, not many results are found for the risk factors of eosinophilic gastroenteritis (EGE).

Some of the risk factors associated with eosinophilic gastroenteritis observed until today are:

  • Hypersensitivity to certain kinds of food products
  • Hypersensitivity to unknown allergens.
  • People with eosinophilic gastroenteritis are prone to chronic digestive issues like abdominal pain, diarrhea, nausea, etc.
  • Eosinophilic gastroenteritis, when found in children, affects their growth by delaying puberty.
  • Although this is a recurring disorder, most people affected by it are also diagnosed with other conditions affecting their health, such as asthma, eczema, rhinitis, etc.
  • This underlying disorder is sometimes associated with autoimmune conditions. According to a few studies, more than 65% of cases reported for EGE include atopic diseases inherited from the families.


Conditions
Dysphagia,Colon resulting in organ dysfunction,Infiltration of the walls of the esophagus
Drugs
Prednisone,Budesonide,Immunosuppressive drugs like azathioprine
Symptoms
Nausea,Diarrhea,Heartburn,Stomach pain,Vomiting,Loss of weight,Bloating

Is there a cure/medications for gastroenteritis, eosinophilic?

Eosinophilic gastroenteritis is a rare digestive disease involving a systematic triad of abnormalities of gastrointestinal function, eosinophilic infiltration of segments of the gastrointestinal tract, and elimination of several diseases with peripheral eosinophilia.
Treatment usually depends on the affected gastrointestinal part.

Treatment of eosinophilic gastroenteritis

  • Dietary therapy is evident to be the first line of therapy. It plays a pivotal role in decreasing the symptoms of eosinophilic gastroenteritis.
  • If the patient has certain food allergies, elimination of such foods from the diet is recommended as they can trigger inflammation.
  • A dietician or nutritionist supervises dietary therapy.
  • Corticosteroids are also an effective class of drugs for eosinophilic gastroenteritis. They function by restricting the activity of the immune system. This decreases the inflammation within the digestive tract. It is highly effective in more than 90% of the cases.
  • The commonly prescribed corticosteroids are prednisolone, budesonide, and fluticasone.
  • Mast cell stabilizers and antihistamines are also preferred treatment options for eosinophilic gastroenteritis. Antihistamines block the inflammatory impacts of histamine, and mast cell stabilizers limit the impacts of definite immune system cells.
  • Surgery is rarely used for treating eosinophilic gastroenteritis. It is evident that dietary therapy and corticosteroids are highly effective for eosinophilic gastroenteritis treatment.


Conditions
Dysphagia,Colon resulting in organ dysfunction,Infiltration of the walls of the esophagus
Drugs
Prednisone,Budesonide,Immunosuppressive drugs like azathioprine
Symptoms
Nausea,Diarrhea,Heartburn,Stomach pain,Vomiting,Loss of weight,Bloating

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