digestive tract
- Bifidobacteria and Mucosal-Associated Invariant T (MAIT) Cells: A New Approach to Colorectal Cancer Prevention
Colorectal cancer is the most preventable form of cancer worldwide. The pathogenesis of colorectal cancer includes gut inflammation, genetic and microbial composition factors. mpairment of the gut mi... Read More
- Diabetes Mellitus and Colon Carcinogenesis: Expectation for Inhibition of Colon Carcinogenesis by Oral Hypoglycemic Drugs
The global deaths due to colorectal cancer and diabetes mellitus have increased by 57% and 90%, respectively. The relationship between various cancers and diabetes mellitus has been shown in multiple ... Read More
- Immunomodulatory Effects of TGF- Family Signaling within Intestinal Epithelial Cells and Carcinomas
TGF- superfamily signaling is responsible for many critical cellular functions including control of cell growth, cell proliferation, cell differentiation, and apoptosis. TGF- appears to be critical ... Read More
- Cannabis Use in Patients Presenting to a Gastroenterology Clinic: Associations with Symptoms, Endoscopy Findings, and Esophageal Manometry
Recreational cannabis use is increasing with its legalization in many states. Animal studies suggest cannabis can reduce transient lower esophageal sphincter relaxations (TLESRS), reflux and vomiting,... Read More
- The Impact of EMG Biofeedback on Evacuation Difficulty Level and Pain Grade During Defecation in Chronically Constipated Elderly Female Patients Due to Dyssynergic Defecation
The purpose of this study was to evaluate the impact of biofeedback therapy on evacuation difficulty level and the pain grade during defecation of elderly female patients with dyssynergic defecation. ... Read More
- Does Irritable Bowel Syndrome Exist Identifiable and Treatable Causes of Associated Symptoms Suggest It May Not
Significant shortcomings in irritable bowel syndrome (IBS) diagnosis and treatment may arise from IBS being an umbrella diagnosis that clusters several underlying identifiable and treatable causes f... Read More
- Proposal for an Organ-Specific Chronic InflammationRemodelingCarcinoma Sequence
An organ-specific chronic inflammationremodelingcarcinoma sequence has been proposed, mainly for the alimentary tract. As representative diseases, gastroesophageal reflux disease, chronic gastritis ... Read More
- Role of Helicobacter pylori in Upper Gastrointestinal Bleeding Among Ischemic Stroke Hospitalizations: A Nationwide Study of Outcomes
Introduction: Helicobacter pylori (H. pylori) is a well-recognized risk factor for upper gastrointestinal bleeding (UGIB). The exposure to tissue plasminogen activator (tPA), anti-platelets, and antic... Read More
- Cytomorphological Characterization of Individual Metastatic Tumor Cells from Gastrointestinal Cancer Patient Lymph Nodes with Imaging Flow Cytometry
The presence or absence of tumor cells within patient lymph nodes is an important prognostic indicator in a number of cancer types and an essential element of the staging process. However, patients wi... Read More
- Referral for Colonoscopy in Patients with Streptococcus bovis Bacteremia and the Association with Colorectal Cancer and Adenomatous Polyps: A Quality Assurance Study
The association between Streptococcus bovis (S. bovis) bacteremia and colorectal cancer is well established. We aimed to review patients with S. bovis bacteremia at our local hospital system and deter... Read More
- Role of Gastric Emptying in Symptoms of Gastroparesis
The symptoms of gastroparesis, such as nausea, vomiting, postprandial fullness, early satiety and abdominal pain, frequently impair the quality of life of the affected individuals. The diagnosis of ga... Read More
- Measuring Microbiome Effectiveness: A Role for Ingestible Sensors
Across the world there is an increasingly heavy burden of noncommunicable diseases related to obesity, mental health, and atopic disease. In a previous publication, we followed the developing idea tha... Read More
- Role of Gastric Electrical Stimulation in the Treatment of Gastroparesis
Introduction: Gastric electrical stimulation (GES) is a surgically implanted treatment option for drug refractory gastroparesis syndromes. Evidence supporting use of GES and the pathophysiology of gas... Read More
- Ccr6 Deficiency Attenuates Spontaneous Chronic Colitis in Winnie
Background: The immune-modulator behaviour of the CCR6/CCL20 axis in multi -system pathophysiology and molecular signalling was investigated at two clinically significant time points, using a Ccr6def... Read More
- Is Bartonella a Cause of Primary Sclerosing Cholangitis A Case Study
The etiology of primary sclerosing cholangitis (PSC) is unknown. I present a case which may be indicative of a causal link between Bartonella infection and PSC. The patient presented with complaints o... Read More
- Status of Brain Imaging in Gastroparesis
The pathophysiology of nausea and vomiting in gastroparesis is complicated and multifaceted involving the collaboration of both the peripheral and central nervous systems. Most treatment strategies an... Read More
- Coadjuvant Anti-VEGF A Therapy Improves Survival in Patients with Colorectal Cancer with Liver Metastasis: A Systematic Review
Background: the presence of liver metastasis in colorectal cancer (CRC) remains one of the most significant prognostic factors. Objective: systematically review the results of studies evaluating the b... Read More
- Gastroparesis in the Pediatric Patient: Children Are Not Little Adults
Although the definition of gastroparesis in children is the same as in adults, there are key differences between gastroparesis in these two populations in presentation, diagnosis, treatment and outcom... Read More
- Hospital-Based Preliminary Observations of Dietary Intake and Physical Activity in Saudi Patients with Colorectal Polyps: A Call for Nutrition Care Integration after Polypectomy Procedure
Aim: In Saudi Arabia, the incidence of colorectal cancer (CRC) is increasing. Lifestyle modification, including diet and physical activity, is as important as the standard procedure of colonoscopy scr... Read More
- Sarcopenia as a Risk Factor of Morbimortality in Colorectal Cancer Surgery
Background: Colorectal cancer (CRC) surgery is associated with high rates of postoperative morbimortality. Sarcopenia has been identified as an independent predictor of these surgical outcomes. Method... Read More