Microvillus inclusion disease is a genetic characteristic that is carried as an autosomal recessive trait. This implies that the disorder is transmitted by a gene on a chromosome that does not have a role in defining a person's gender.
- Both males and females can be infected, though it appears to affect females more frequently.
- Because this gene is recessive, both parents have it to pass the condition on to their child.
- More than one kid is impacted in some households.
- Those with a family background of microvillus inclusion disease may benefit from genetic counseling when planning for children, but there is no way to anticipate or control microvillus inclusion disease at this time.
- Microvillus inclusion disease symptoms typically appear within hours or days of birth; however, symptoms may appear later (about two months after birth) and/or be less severe.
Cure for Microvillus Inclusion Disease
- Various medicines have been tried in the past to control or counteract extreme diarrhea, but none have proven beneficial.
- Infants with microvillus inclusion disease require nutritionally balanced formulas administered directly into the veins (intravenously), sometimes referred to total parenteral nutrition (TPN).
- TPN can help a baby's health stabilize, but it is not always a good long-term treatment.
- TPN can damage the liver and raise the infection risk over time.
- When TPN causes severe difficulties, intestine transplantation is frequently the best option.
Abdominal distention,Abnormal renal physiology,Abnormality of small intestinal villus morphology,Global developmental delay,Hypovolemia,Nephrocalcinosis,Pruritus,Villous atrophy
Total parenteral nutrition (TPN),Antisecretagogue agents (eg, somatostatin, octreotide, loperamide, chlorpromazine) can reduce the stool output
Watery stool,Abnormal shape of small intestinal villus,Renal functional abnormality,Distended abdomen,Villous degeneration,Skin itching,Retarded psychomotor development,Depleted blood volume