Hutchinson Weber Peutz syndrome/Peutz-Jeghers syndrome is a genetic condition that causes non-cancerous growths to develop in the digestive system.
Risk factors of Hutchinson Weber Peutz syndrome include,
- It is an autosomal dominant genetic condition caused by mutations in the STK11/LKB1 gene.
- The condition can be passed from generation to generation in a family.
- When only a single copy of an abnormal gene is necessary for the appearance of the disease, dominant genetic disorders occur.
- The abnormal gene can be inherited from either parent, or can be the result of a new mutation in the affected individual.
- There are 50% chances of passing the abnormal gene from an affected parent to an offspring for each pregnancy.
- The risk of developing Hutchinson Weber Peutz syndrome is the same for males and females.
- Individuals with this genetic condition have an increased risk of developing cancer and polyps.
- It is possible that there are other genes that could cause PJS that have not yet been discovered.
Hamartomous polyps in oral cavity and nostrils
Constant surveilance and test,Symptomatic treatment
Characteristic dark-colored spots,Development of hamartomatous polyps,Small bowel obstruction (blockage),Gastrointestinal bleeding,Anemia,Stomach pain,Intussusception of the small bowel